This blog post is intended for people who refer to chemical names/symbols and synonyms in databases like PubMed and PubChem, or in their own scientific papers. There is a similar post for gene symbols and names.
During the research and publishing process, scientists need to refer to their chemicals-of-interest. While there are standardized nomenclatures (IUPAC, SMILES, InChITM, etc.), different labs sometimes use different names for the same chemical.
The NCBI PubChem project has set up a system to identify and correlate these various names as well as ‘alias’, ‘synonym’, or ‘also known as’ terms that have been used in the literature.
This blog post is intended for people who refer to gene symbols or names in databases such as Gene, ClinVar, or PubMed. There is a similar post for chemical names and symbols.
During the research and publishing process, scientists need to refer to their genes-of-interest. However, different labs sometimes use different gene symbols to refer to the same gene. As you can imagine, this leads to confusion.
To standardize the use of terms, the HUGO Gene Nomenclature Committee (HGNC) sets official gene symbols and names. The NCBI Gene resource reports these official gene symbols and names, as well as additional symbols and names that are included on related sequence records for the same gene or from submitted GeneRIFs.