ClinVar Unveils New, More Intuitive Variation Display

ClinVar, NCBI’s database of clinically relevant genetic variations with supporting evidence, has redesigned its variation display, and welcomes your feedback. The new Variation in ClinVar (VCV) pages provide a better-organized, more-intuitive web display that makes it easy to quickly find the information you need.

In this blog post, we’ll take you through the new design using the example of a coding region variant (VCV000256160.1) in the ABCB4 gene.

ClinVar variation page alpha view. Accession number & feedback tab are circled to highlight them.

The redesign brings the most important information to the top of the display. There are two new fields: (1) the VCV accession number and version used to cite the record, and (2) a short description of the variation (e.g., 11.3 kb deletion, or haplotype) to make it easy to quickly see what type of variation the record represents.

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NIH Data Hackathon on campus – January 22-24, 2018

From January 22-24, 2018, the NCBI will help with a data science hackathon on the NIH campus in Bethesda, MD. The hackathon will focus on general data science analyses, including text, image and sequence processing. This event is for researchers, including students and postdocs, who have already engaged in the use of large datasets or in the development of pipelines for analyses from high-throughput experiments. Some projects are available to other non-scientific developers, mathematicians, or librarians.

The event is open to anyone selected for the hackathon and willing to travel to the NIH campus (see below).  Applications are due Friday, December 22nd, 2017 by 9 pm EST.

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January 10 NCBI Minute: QuickBLASTP — a program for rapidly finding high-scoring protein matches in large databases

In the next NCBI Minute on Wednesday, January 10, 2018, NCBI staff will demonstrate the new QuickBLASTP service that can search large databases at least 10X faster than traditional protein-protein BLAST (blastp). You will learn about the strategy QuickBLASTP uses to speed up the search. You will also see how to use the new QuickBLASTP service on the NCBI web BLAST site and how to access and run the standalone kblastp demonstration release.

Date & time: Wed, Jan 10, 2018 12:00 PM – 12:30 PM EST

After registering, you will receive a confirmation email with information about attending the webinar. A few days after the live presentation, you can view the recording on the NCBI YouTube channel. You can learn about future webinars on the Webinars and Courses page.

Summer 2017 NCBI Hackathon Products

This blog post is for researchers, students, and postdocs, as well as non-scientific developers, mathematicians and librarians.

This summer, we were quite busy running and cohosting hackathons. These events educate participants, allow for networking among computational biologists and produce bioinformatics software prototypes.  Read on for a review of products from our Summer 2017 hackathons.

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