RefSeq release 88 is now accessible online, via FTP and through NCBI’s programming utilities. This full release incorporates genomic, transcript, and protein data available, as of May 14, 2018. It contains 160,224,355 records, including 110,333,800 proteins, 22,461,378 RNAs, and sequences from 79,448 organisms. The release is in several directories as a complete dataset and as divided by logical groupings.
This release incorporates dbSNP release 151, which nearly doubles the number of SNPs annotated on the human GRCh38 genome, with matching increases in the size of the human nucleotide flatfile (.gbff) records.
Starting in November 2018, SNP variation features will no longer be in RefSeq genome assembly records. The RefSeq release notes have information about this change.
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