Release 12.0 of the NCBI protein profile Hidden Markov models (HMMs) used by the Prokaryotic Genome Annotation Pipeline (PGAP) is now available for download. You can search this collection against your favorite prokaryotic proteins to identify their function using the HMMER sequence analysis package.
The 12.0 release contains:
- 15,849 HMMs maintained by NCBI
- 271 new HMMs since release 11.0
- 1,248 HMMs with better names, EC numbers, Gene Ontology (GO) terms, gene symbols or publications
GO terms associated with HMMs are now propagated to CDSs and proteins annotated with PGAP. In case you missed it, see our previous blog post on this topic.
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