Exploring 3D Molecular Structures with iCn3D
This workshop concluded on October 27, 2022. Workshop materials are available here.
The amount of biomolecular structure data produced by researchers is growing rapidly and helping push scientific discovery. Knowledge of biomolecular structure helps scientists understand how the structure works and this knowledge can be used to influence function, predict binding partners, and understand biological pathways. As such, researchers in life sciences can benefit from an increased understanding of biomolecular structure and resources that build upon structural data. In this workshop, we will use iCn3D, a free, web-based tool supported by NCBI that allows you to explore the structure of a biomolecule at an atomistic level.
Throughout this online, interactive workshop we will cover:
- Where to find information on motifs, domains, and similar structures
- How to analyze 3D structure and highlight important features like active site residues, point mutations, and binding partners
- How to compare AlphaFold and PDB Files
- How to save and share visualization files
Please note, this workshop was designed for life scientists with some (intermediate) background in structural biology. We will not be performing structure prediction, molecular docking, or molecular dynamics simulations.