MutaGene is a new, freely available resource for understanding the mutagenic factors contributing to tumor development.
Cancer arises from multiple changes in the DNA that can be caused by various extrinsic factors, such as sunlight and tobacco smoking, and intrinsic factors, such as the body’s own defense mechanisms fighting against viral infection or faulty DNA copying and repair molecular machinery. Knowing what factors contribute to the accumulation of mutations in a given cancer patient can be crucial for prognosis and identifying correct treatment.