Enhancements to ClinVar Website Now Live

Enhancements to ClinVar Website Now Live

Important Note: Support for both the old XML formats has been extended through the end of June 2024.

As previously announced, we updated the ClinVar website as part of our effort to better support the display of submitted somatic variation data. 

What changed? 

  • Updated ClinVar search results
    • Germline / Somatic origin filter
    • Somatic Classification and Review Status summary
  • Screenshot of the ClinVar somatic search.Updated Variant (VCV)  record page
    • Includes both Germline and Somatic data for the same variant
    • Switch to turn on/off Somatic or Germline information
  • Screenshot of ClinVar search results page updated filter Efetch command within E-utilities 
    • By default, the E-utilities efetch command now retrieves the new XML with support for somatic variant
    • Include the parameter old_xml=T in EFetch calls to get the old XML
    • Support for both new and old XML formats through the end of March 2024

Important note: These screenshots include test data and is not intended to represent real variants. But we are ready for your submissions of somatic variation data! 

Learn more

For more information about our recent updates to the ClinVar website, check out our release notes 

Stay up to date

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Questions?

If you have questions or would like to provide feedback, please reach out to us at clinvar@ncbi.nlm.nih.gov. 

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