RefSeq release 94 with MANE and RefSeq Select markup, protein name evidence, and improved [Candida] auris assembly


RefSeq release 94 is now available through NCBI web services, FTP and through NCBI’s Entrez programming utilities, E-utilities.

This full release incorporates genomic, transcript, and protein data available, as of May 13, 2019 and contains 200,311,267 records, including 141,839,334 proteins, 26,534,602 RNAs, and sequences from 91,873 organisms. The release is provided in several directories as a complete dataset and also as divided by logical groupings.

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Human genome annotation will be updated every 2 months


NCBI will be updating the human genome RefSeq annotation more frequently to incorporate improvements made to genes and transcripts by RefSeq curation experts. Faster updates will allow us to include the latest datasets.

In the past, we’ve produced a full re-annotation of the human genome about once a year. The last full annotation, Homo sapiens Annotation Release 109, was in March 2018. A full annotation is produced by two main processes:

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Expanded accession formats appear in RefSeq release 93


RefSeq release 93 is accessible online, via FTP and through NCBI’s Entrez programming utilities, E-utilities.

This full release incorporates genomic, transcript, and protein data available as of March 13, 2019. It contains 192,722,653 records, including 135,670,032 proteins, 25,840,272 RNAs, and sequences from 88,816 organisms.

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New RefSeq annotations for big brown bat, peregrine falcon and more


Hibernating brown bat

In January and February, the NCBI Eukaryotic Genome Annotation Pipeline released new annotations in RefSeq for the following organisms:

  • Aphis gossypii (cotton aphid)
  • Balaenoptera acutorostrata scammoni (minke whale)
  • Bombyx mandarina (wild silkworm)
  • Chelonia mydas (green sea turtle)
  • Corapipo altera (white-ruffed manakin)
  • Empidonax traillii (willow flycatcher)
  • Eptesicus fuscus (big brown bat)
  • Eumetopias jubatus (Steller sea lion)
  • Falco cherrug (Saker falcon)
  • Falco peregrinus (peregrine falcon)
  • Marmota flaviventris (yellow-bellied marmot)
  • Monomorium pharaonis (pharaoh ant)
  • Neopelma chrysocephalum (saffron-crested tyrant-manakin)
  • Ovis aries (sheep)
  • Pipra filicauda (wire-tailed manakin)
  • Rhopalosiphum maidis (corn leaf aphid)
  • Solanum pennellii (eudicot)
  • Tupaia chinensis (Chinese tree shrew)
  • Vigna unguiculata (cowpea)
  • Vombatus ursinus (common wombat)
  • Xiphophorus couchianus (Monterrey platyfish)

See more details on the Eukaryotic RefSeq Genome Annotation Status page.

RefSeq release 92 updates 10,000 human transcripts


RefSeq release 92 is accessible online, via FTP and through NCBI’s Entrez programming utilities, E-utilities.

This full release incorporates genomic, transcript, and protein data available, as of January 4, 2019 and contains 185,738,687 records, including 130,366,644 proteins, 25,088,890 RNAs, and sequences from 86,867 organisms. The release is provided in several directories as a complete dataset and as divided by logical groupings.

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Join NCBI at PAG in San Diego, January 12–16, 2019


Next week, NCBI staff will attend the Plant and Animal Genome (PAG) Conference. We have several activities planned, including 1 booth (#223), 4 workshops, 1 talk and 2 posters.

Read on to learn more about what you can look forward to if you’re attending PAG this year. (Note: The listed times are Pacific time.)

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RefSeq release 91 is public


RefSeq release 91 is accessible online, via FTP and through NCBI’s Entrez programming utilities, E-utilities.

This full release incorporates genomic, transcript, and protein data available as of November 5, 2018. It contains 179,672,083 records, including 125,530,811 proteins, 24,447,570 RNAs, and sequences from 85,308 organisms.

The release is provided in several directories as a complete dataset and as divided by logical groupings.

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