Tag: RefSeq

Now Available: RefSeq Release 236

Now Available: RefSeq Release 236

RefSeq release 236 is now available online and from the FTP site! You can access RefSeq data through NCBI Datasets. The release is provided in several directories as a complete dataset and also as divided by logical groupings.    

What’s included in this release? 

As of July 6, 2026, this full release incorporates genomic, transcript, and protein data containing:   

  • 629,953,391 records  
  • 482,864,455 proteins  
  • 83,806,434 RNAs  
  • Sequences from 182,465 organisms  

Continue reading “Now Available: RefSeq Release 236”

Now Available! NCBI Hidden Markov Models (HMM) Release 20.0

Now Available! NCBI Hidden Markov Models (HMM) Release 20.0

Download release 20.0 of the NCBI protein profile Hidden Markov models (HMMs) used by the Prokaryotic Genome Annotation Pipeline (PGAP). You can search this collection against your favorite prokaryotic proteins to identify their function using the HMMER sequence analysis package. 

What’s new? 

Release 20.0 contains: 

  • 18,950 HMMs maintained by NCBI 
  • 497 new HMMs since release 19.0 

Continue reading “Now Available! NCBI Hidden Markov Models (HMM) Release 20.0”

Now Available: RefSeq Release 235

Now Available: RefSeq Release 235

RefSeq release 235 is now available online and from the FTP site! You can access RefSeq data through NCBI Datasets. The release is provided in several directories as a complete dataset and also as divided by logical groupings.    

What’s included in this release? 

As of May 11, 2026, this full release incorporates genomic, transcript, and protein data containing:   

  • 616,942,961 records  
  • 473,570,633 proteins  
  • 81,124,747 RNAs  
  • Sequences from 180,620 organisms  

Continue reading “Now Available: RefSeq Release 235”

New Data Available! Access Hantavirus Sequences at NCBI

New Data Available! Access Hantavirus Sequences at NCBI

Sequence data from the recent Andes hantavirus outbreak are now available through NLM’s NCBI resources, NCBI Virus web interface and NCBI Datasets command-line tool. These data were submitted by the University Hospitals of Geneva. 

Access through NCBI Virus 

To find sequence records from 2026, search for “Orthohantavirus andesense” in NCBI Virus and apply the “Collection Date” filter. To get a quick overview of Andes hantavirus data available through GenBank, visit the NCBI Virus Outbreak Statistics page (select Andes hantavirus) which shows the collection location and host for recently collected samples.   Continue reading “New Data Available! Access Hantavirus Sequences at NCBI”

Now Available: Updated Bacterial and Archaeal Reference Genome Collection

Now Available: Updated Bacterial and Archaeal Reference Genome Collection

Download the updatedbacterial and archaeal reference genome collection! We built this collection of 23,063 genomes by selecting the “best” genome assembly for each species among the 450,000+ prokaryotic genomes inRefSeq.  

What’s new?  
  • Two species are represented in this collection for the first time  
  • 283 species are represented by a better assembly 
  • Six species were removed because of changes in NCBI Taxonomy or uncertainty in their species assignment  

Continue reading “Now Available: Updated Bacterial and Archaeal Reference Genome Collection”

Now Available: RefSeq Release 233

Now Available: RefSeq Release 233

RefSeq release 233 is now available online and from the FTP site! You can access RefSeq data through NCBI Datasets. The release is provided in several directories as a complete dataset and also as divided by logical groupings.   

What’s included in this release? 

As of January 26, 2026, this full release incorporates genomic, transcript, and protein data containing:  

  • 578,285,616 records 
  • 442,943,508 proteins 
  • 76,278,418 RNAs 
  • Sequences from 174,157 organisms 

Continue reading “Now Available: RefSeq Release 233”

Now Available! NCBI Hidden Markov Models (HMM) Release 19.0

Now Available! NCBI Hidden Markov Models (HMM) Release 19.0

Download release 19.0 of the NCBI protein profile Hidden Markov models (HMMs) used by the Prokaryotic Genome Annotation Pipeline (PGAP). You can search this collection against your favorite prokaryotic proteins to identify their function using the HMMER sequence analysis package.  

What’s new?  

Release 19.0 contains:  

  • 18,513 HMMs maintained by NCBI  
  • 465 new HMMs since release 18.0  

Continue reading “Now Available! NCBI Hidden Markov Models (HMM) Release 19.0”

An Updated Bacterial and Archaeal Reference Genome Collection is Available!

An Updated Bacterial and Archaeal Reference Genome Collection is Available!

Download the updated bacterial and archaeal reference genome collection! We built this collection of 22,420 genomes by selecting the “best” genome assembly for each species among the 450,000+ prokaryotic genomes in RefSeq. 

What’s new? 
  • One species is represented in this collection for the first time 
  • 323 species are represented by a better assembly
  • Six species were removed because of changes in NCBI Taxonomy or uncertainty in their species assignment 

Continue reading “An Updated Bacterial and Archaeal Reference Genome Collection is Available!”

An Updated Bacterial and Archaeal Reference Genome Collection is Available!

An Updated Bacterial and Archaeal Reference Genome Collection is Available!

Download the updated bacterial and archaeal reference genome collection! We built this collection of 22,082 genomes by selecting the “best” genome assembly for each species among the 440,000+ prokaryotic genomes in RefSeq. 

What’s new? 
  • 28 species are represented in this collection for the first time 
  • 228 species are represented by a better assembly 
  • Six species were removed because of changes in NCBI Taxonomy or uncertainty in their species assignment 

Continue reading “An Updated Bacterial and Archaeal Reference Genome Collection is Available!”